Sharing the ups and downs of his childhood experiences as one of eleven children in Minnesota, Louie crafted comedy routines that rang true for his early club audiences. While reducing his audiences to helpless fits of laughter, Louie's routines led him from his career as a counselor to troubled children to the first-place trophy at the 1981 Midwest Comedy Competition. Henny Youngman, who hosted the competition, recognized the diamond-in-the-rough genius of the young comic and hired him as a writer.
Johnny Carson invited Louie to make his national television debut on The Tonight Show in 1984 and the rest is history. Leno, Letterman, Comic Relief and ShowTime and HBO specials followed, making Louie a household name and opening doors for him as an actor.
He has guest-starred in sitcoms like Grace Under Fire and dramas like Touched by an Angel and Chicago Hope. He is also the host of the riotous Comedy Showcase, the late-night series that follows Saturday Night Live.
In 1995 Louie put his creative energies to work on the Saturday morning animated series Life With Louie. The long-running series based on Louie's own childhood and his life with his father won three Humanities Prizes for writing on a children's animated series, making him the only three-time recipient of this award. It also earned a Genesis Award for its depiction of proper treatment of animals and, most significantly, two Emmy Awards.
Louie's best-selling books include Dear Dad - Letters From An Adult Child, a collection of alternately touching and outrageous letters from Louie to his late father, and Good-Bye Jumbo, Hello Cruel World, self-help for those who struggle with self-esteem issues, as only an award winning comedian could write it.